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Updated resources for exploring experimentally-determined PDB structures and Computed Structure Models at the RCSB

Stephen K Burley1,2,3,4,5,6, Rusham Bhatt1,2, Charmi Bhikadiya5

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Summary
This summary is machine-generated.

The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) now offers enhanced tools and visualizations for over 227,000 biostructures and 1 million protein models. Explore similar proteins with new features for structural biology research.

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Area of Science:

  • Structural Biology
  • Bioinformatics
  • Computational Biology

Background:

  • The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) is the US data center for the global Protein Data Bank (PDB) archive.
  • It provides access to experimentally determined atomic-level 3D biostructures and computed protein models via its RCSB.org web portal.

Purpose of the Study:

  • To report substantial additions to the tools and visualization features available at RCSB.org.
  • To enhance user experience for exploring biostructure data and computed protein models.

Main Methods:

  • Integration of new tools and visualization features into the RCSB.org platform.
  • Organization of query results by redundancy-reduced Groups.
  • Development of summary pages for exploring groups of similar proteins.
  • Introduction of new programmatic tools and enhanced training opportunities.

Main Results:

  • RCSB.org now provides access to over 227,000 experimentally determined 3D biostructures.
  • Over 1 million Computed Structure Models (CSMs) of proteins are available, including those for humans, model organisms, pathogens, and crop plants.
  • New features support 3D structure motif searches and facilitate exploration of protein groups.

Conclusions:

  • The enhanced RCSB.org portal offers expanded resources for structural biology research.
  • New features improve data accessibility, exploration, and programmatic access to biostructure information.
  • These advancements support a wide range of biological research, including studies on human health and climate change adaptation.