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Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

221
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
221
Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Related Experiment Video

Updated: Jun 6, 2025

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
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Developmental Outcomes of Very Preterm Infants Conceived Through In Vitro Fertilization.

Taylor Badger1, Emma Johns2, Teresa Wilson3

  • 1Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL, USA.

Archives of Medical Research
|November 28, 2024
PubMed
Summary
This summary is machine-generated.

Very preterm infants conceived via in vitro fertilization (IVF) show similar neurodevelopmental outcomes compared to spontaneously conceived infants. This finding offers reassurance for those considering IVF for conception.

Keywords:
In vitro fertilizationNeurodevelopmental outcomePreterm birthPreterm infant

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Area of Science:

  • Neonatology
  • Reproductive Medicine
  • Developmental Pediatrics

Background:

  • Assisted reproductive technology, including in vitro fertilization (IVF), is increasingly used.
  • Concerns exist regarding potential differences in outcomes for infants conceived via IVF, particularly those born very preterm.
  • Understanding these outcomes is crucial for parental counseling and clinical management.

Purpose of the Study:

  • To compare in-hospital and neurodevelopmental (ND) outcomes of very preterm infants conceived spontaneously versus those conceived via IVF.
  • To provide data to inform individuals considering IVF conception.

Main Methods:

  • A 10-year retrospective study analyzed a large regional population.
  • IVF-conceived infants born before 32 0/7 weeks gestational age were matched 1:2 to control infants conceived spontaneously.
  • In-hospital and neurodevelopmental data were collected and analyzed.

Main Results:

  • 27 very preterm IVF-conceived infants were compared to 54 controls.
  • IVF infants were more likely to be born to older mothers; other demographic factors were similar.
  • In-hospital outcomes were comparable, with no significant differences in neurodevelopmental outcomes through 24 months.

Conclusions:

  • Very preterm infants conceived via IVF demonstrate similar in-hospital and neurodevelopmental outcomes compared to spontaneously conceived very preterm infants.
  • This study provides reassuring evidence for individuals considering IVF.
  • Further research may explore long-term outcomes beyond 24 months.