Percutaneous Coronary Intervention and Long-Term Management of Acute Myocardial Infarction in a Hemophilia Patient:...

Area of Science:

• Cardiology
• Hematology

Background:

• Hemophilia A patients present unique challenges for managing cardiovascular diseases due to bleeding risks.
• Acute coronary syndrome (ACS) requires timely and effective intervention, which may be complicated by bleeding disorders.

Observation:

• A 55-year-old male with hemophilia A experienced recurrent chest pain after a coagulation factor overdose.
• Coronary imaging revealed moderate stenosis, progressing to severe thrombotic occlusion requiring stent placement.
• The patient received dual antiplatelet therapy followed by single antiplatelet therapy under conventional hemophilia management.

Findings:

• Successful percutaneous coronary intervention (PCI) with a bare metal stent was performed.
• The patient remained event-free for 5 years on single antiplatelet therapy (clopidogrel) with standard hemophilia care.
• No major bleeding complications were reported during the management of ACS.

Implications:

• Invasive coronary interventions and post-procedural management for ACS are feasible in hemophilia A patients using standard protocols.
• Maintaining usual coagulation factor doses alongside antiplatelet therapy appears safe and effective.
• This case supports the integration of cardiovascular care within hemophilia management protocols.