Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

337
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
337
Computed Tomography01:10

Computed Tomography

4.3K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.3K
Positron Emission Tomography01:29

Positron Emission Tomography

4.0K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.0K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

257
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
257
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

570
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
570
High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

479
The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte...
479

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Codonopsis pilosula (Dangshen) decoction promotes NR2F2-dependent pulmonary endothelial repair in an H9N2-induced lung injury model" [J. Ethnopharmacol. 370 (2026) 122078].

Journal of ethnopharmacology·2026
Same author

Glycocalyx disruption mediates HP-PRRSV-induced microvascular endothelial dysfunction and underlies astragalus polysaccharide's antiviral efficacy.

Open veterinary journal·2026
Same author

Haplotype-resolved genome assembly sheds light on the evolutionary history of autohexaploid Tripidium arundinaceum.

Nature communications·2026
Same author

Anterior Cingulate Cortex Mediates State-Dependent Prioritization of Distressed Conspecifics.

Brain sciences·2026
Same author

Visualization and detection of ciliary beating frequency in human airway organoids based on image correlated methods for drug screening.

Biochemical and biophysical research communications·2026
Same author

The expression landscape and clinical significance of cancer-specific RNA transcripts across human cancers.

Journal of translational medicine·2026

Related Experiment Video

Updated: Jun 6, 2025

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
11:27

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2

Published on: December 8, 2016

12.2K

Photon-counting detector CT provides superior subsolid nodule characterization compared to same-day

Jinhua Wang1, Zhicheng Huang2, Zhenchen Zhu1

  • 1Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

European Radiology
|November 28, 2024
PubMed
Summary

Photon-counting detector (PCD) CT offers improved image quality and radiation dose reduction for subsolid nodule (SSN) characterization compared to energy-integrating detector (EID) CT. PCD CT enhances visualization of SSN features, aiding in more precise diagnosis.

Keywords:
Energy-integrating detectorImage qualityPhoton-counting detectorRadiation doseSubsolid nodule

More Related Videos

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

2.3K
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

12.5K

Related Experiment Videos

Last Updated: Jun 6, 2025

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
11:27

Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2

Published on: December 8, 2016

12.2K
Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

2.3K
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

12.5K

Area of Science:

  • Radiology and Medical Imaging
  • Computed Tomography Technology
  • Pulmonary Nodule Detection

Background:

  • Subsolid nodules (SSNs) require precise characterization for accurate diagnosis and management.
  • Conventional energy-integrating detector (EID) CT has limitations in visualizing subtle SSN characteristics.
  • Photon-counting detector (PCD) CT represents a technological advancement with potential for improved imaging performance.

Purpose of the Study:

  • To compare the image quality and performance of PCD CT versus EID CT in identifying SSN characteristics.
  • To evaluate the effectiveness of PCD CT in visualizing subtle features of SSNs.
  • To assess the potential of PCD CT for radiation dose reduction in SSN imaging.

Main Methods:

  • Prospective inclusion of participants with SSNs undergoing same-day EID CT and PCD CT.
  • Review of 1.0 mm EID CT and 1.0 mm, 0.4 mm, and 0.2 mm PCD CT images.
  • Assessment of objective image noise, subjective image quality (Likert scale), and specific SSN characteristics (lobulation, spiculation, etc.).

Main Results:

  • PCD CT significantly reduced radiation dose compared to EID CT (1.79 vs 2.17 mSv).
  • PCD CT demonstrated significantly lower objective image noise and higher subjective image quality than EID CT.
  • PCD CT enhanced visualization of subtle SSN characteristics, with 0.4 mm thickness offering optimal resolution-perceived quality balance.

Conclusions:

  • PCD CT outperforms conventional EID CT in image quality and SSN characteristic visualization.
  • PCD CT facilitates significant radiation dose reduction for patients undergoing CT scans.
  • PCD CT enables more precise characterization of subsolid nodules, improving diagnostic accuracy.