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PI-QUAL version 2 image quality categorisation and inter-reader agreement compared to version 1
Kang-Lung Lee1,2,3, Iztok Caglic4, Po-Hsiang Liao3,5,6
1Department of Radiology, University of Cambridge, Cambridge, UK.
Objectives:
Prostate imaging quality (PI-QUAL) was developed to standardise the evaluation of prostate MRI quality and has recently been updated to version 2. This study aims to assess inter-reader agreement for PI-QUAL v1 and v2 scores and investigates changes in MRI quality score categories.
Materials And Methods:
The study retrospectively analysed 350 multiparametric MRI (mpMRI) scans. Two expert uroradiologists independently assessed mpMRI quality using PI-QUAL v1 and v2 guidelines. Biparametric MRI (bpMRI) categorisation based on PI-QUAL v2 included only T2WI and diffusion-weighted imaging (DWI) results. Inter-reader agreement was determined using percentage agreement and kappa, and categorisation comparisons were made using the chi-square test.
Results:
Substantial inter-reader agreement was observed for the overall PI-QUAL v1 score (κ = 0.64) and moderate agreement for v2 mpMRI (κ = 0.54) and v2 bpMRI scores (κ = 0.57). Inter-reader agreements on individual sequences were similar between v1 and v2 (kappa for individual sequences: T2WI, 0.46 and 0.49; DWI, 0.66 and 0.70; DCE, 0.71 and 0.61). Quality levels shifted from predominantly "optimal" in v1 (65%) down to "acceptable" using v2 (55%); p < 0.001. The addition of DCE increased the proportion of cases with at least "adequate" quality at mpMRI (64%) compared to bpMRI (30%); p < 0.001.
Conclusion:
This study shows consistent inter-reader agreement between PI-QUAL v1 and v2, encompassing overall and individual sequence categorisation. A notable shift from "optimal" to "acceptable" quality was demonstrated when moving from v1 to v2, with DCE tending improving quality from "inadequate" (bpMRI) to "acceptable" (mpMRI).
Key Points:
Question What are the agreement levels of image quality of prostate MRI by using PI-QUAL v1 and v2? Findings Inter-reader agreement based on PI-QUAL v1 and v2 is comparable. Dynamic contrast enhancement (DCE) enables an overall shift from inadequate quality (at bpMRI) to acceptable quality (mpMRI). Clinical relevance The inter-reader agreement on PI-QUAL v1 and v2 is equivalent. PI-QUAL v2 assesses prostate bpMRI as well as mpMRI quality. Transitioning from inadequate to acceptable between v2-bpMRI and v2-mpMRI highlights the role of DCE as an "image quality safety net."
