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Endoscopic cystostomy and biliary sphincterotomy for choledochoceles: A pediatric case series
Michelle Saad1,2, Maisam Abu-El-Haija1,2, Tom K Lin1,2
1Division of Gastroenterology, Hepatology and Nutrition Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.
Insights
Endoscopic management of choledochoceles (type III choledochal cysts) in children offers a successful treatment option. This minimally invasive approach led to sustained symptom resolution and radiographic improvement in pediatric patients.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Endoscopic Procedures
Background:
- Choledochoceles, a type of choledochal cyst, present varied management challenges in pediatric patients.
- Symptoms often include abdominal pain and pancreatitis, necessitating effective treatment strategies.
Purpose of the Study:
- To evaluate the efficacy of endoscopic management for pediatric choledochoceles.
- To assess the long-term outcomes of cystostomy and biliary sphincterotomy in children with choledochoceles.
Main Methods:
- Retrospective review of three pediatric patients (ages 12-13) with symptomatic choledochoceles.
- Endoscopic cystostomy and biliary sphincterotomy performed for choledochal cyst treatment.
- Pre- and post-procedure imaging (MRI) and tumor marker assessment.
Main Results:
- Successful endoscopic treatment of choledochoceles in all three pediatric patients.
- Sustained clinical improvement and radiographic resolution at 2-year follow-up.
- Normal tumor markers post-procedure, indicating no malignancy.
Conclusions:
- Endoscopic management with cystostomy and biliary sphincterotomy is a viable therapeutic option for pediatric choledochoceles.
- This approach can achieve sustained symptom resolution and radiographic healing.
- Malignancy risk in choledochoceles is rare, supporting less invasive treatment modalities.
Abstract:
Management of choledochoceles (type III choledochal cysts) in children varies. We highlight the potential role of endoscopic management of choledochoceles with cystostomy and biliary sphincterotomy through a series of three successfully treated pediatric patients aged 12-13 at our tertiary center. Patients presented with symptoms including abdominal pain and pancreatitis. Choledochoceles were identified by preprocedure imaging on magnetic resonance imaging, with sizes ranging between 7 and 15 mm in maximal diameter. Histology revealed two choledochoceles lined by biliary epithelium and one by intestinal epithelium. Clinical improvement was sustained at a 2-year follow-up, with radiographic resolution on repeat imaging and normal tumor markers. We conclude that endoscopic management of choledochoceles with cystostomy and biliary sphincterotomy is a therapeutic option in children and can lead to sustained resolution of associated symptoms. While there is some lifetime risk of malignancy with choledochal cysts, malignancy in choledochoceles is rare.
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