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Updated: May 10, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
[In-hospital management of intracerebral hemorrhage]
Jochen Sembill1, Stefan Schwab2
1Klinik für Neurologie, Universitätsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland. jochen.sembill@uk-erlangen.de.
Insights
Aggressive treatment bundles, including blood pressure control and reversing anticoagulation, improve outcomes for patients with intracerebral hemorrhage (ICH). Early intervention and prognostic assessment are key for managing this medical emergency.
Area of Science:
- Neurology
- Neurosurgery
- Emergency Medicine
Context:
- Intracerebral hemorrhage (ICH) presents a critical medical emergency with significant morbidity and mortality.
- Effective in-hospital care is crucial for improving patient outcomes.
Purpose:
- To review the current scientific evidence on in-hospital management strategies for intracerebral hemorrhage.
- To analyze available treatment options and their efficacy.
Summary:
- Acute therapy focuses on preventing hematoma expansion, utilizing CT markers, initial volume, anticoagulation status, and time to treatment.
- Key interventions include prompt blood pressure reduction to <140 mmHg systolic, immediate anticoagulation reversal, and optimized intensive care.
- External ventricular drainage and intraventricular fibrinolysis manage intraventricular hemorrhage; minimally invasive surgery may benefit lobar ICH.
Impact:
- Recent evidence supports aggressive, evidence-based therapeutic approaches for ICH.
- Individual and combined treatment measures demonstrate reliable efficacy.
- Informed treatment decisions are facilitated by realistic prognostic assessments.
Background:
Intracerebral hemorrhage (ICH) is a medical emergency with high morbidity and mortality. General and specific therapeutic approaches aim to improve the patient's outcome.
Objectives:
The objective of this article is to present the current scientific state regarding the in-hospital care of patients with ICH.
Materials And Methods:
This narrative review presents and analyzes the current evidence regarding treatment options for ICH.
Results:
The primary focus of acute therapy is to prevent the prognostically unfavorable enlargement of the hematoma. This is associated with specific computed tomographic markers, as well as the initial hematoma volume, the use of anticoagulants, and a shorter time from symptom onset. An elevated blood pressure should be promptly and precisely lowered to a systolic value below 140 mm Hg, and the inhibition of coagulation must be immediately antagonized. This should be constituted into a treatment bundle with optimal adjustment of vital parameters and implementation of basic intensive care measures. Intraventricular hemorrhage can be effectively treated by external ventricular drainage and intraventricular fibrinolysis, with or without additional lumbar drainage. Minimally invasive procedures for hematoma removal have the potential to improve outcomes in lobar ICH. A realistic prognostic assessment forms the basis for informed treatment decisions regarding ICH.
Conclusions:
In recent years, the evidence supporting aggressive therapeutic approaches in ICH has become increasingly robust, with reliable results now available regarding the efficacy of individual or combined measures.
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