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High-Frequency Cognitive Control Training for Depression: Case Report.

Yannick Vander Zwalmen¹, Kristof Hoorelbeke¹, David Demeester^1,2

¹Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium.

JMIR Formative Research

|November 29, 2024

Summary

Cognitive control training (CCT) improved cognitive function and reduced depressive symptoms in a case study. Extended training may offer further benefits, but its impact on emotion regulation requires further investigation.

Keywords:

CCT case report cognitive control training cognitive function depression digital health memory training prevention recurrence relapse task performance working memory

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Area of Science:

Neuroscience
Psychology
Clinical Medicine

Background:

Cognitive control training (CCT) is a potential preventative intervention for major depressive disorder.
Mechanisms and long-term effects of CCT require further elucidation.

Purpose of the Study:

To investigate cognitive and affective transfer effects after an extensive CCT regimen.
To explore the impact of a high volume of training sessions on cognitive and emotional well-being.

Main Methods:

A case report involving a participant undergoing 55 CCT sessions over one year.
Utilized reliable change indices on self-report questionnaires for cognitive and affective functioning.
Included thematic analysis of an in-depth interview regarding CCT adherence and user experience.

Main Results:

Significant improvements in cognitive task performance (24% to 61% accuracy) maintained at follow-up.
Reductions in depressive symptoms (Beck Depression Inventory-II score from 23 to 3) and burnout.
Variable effects on emotion regulation; no change in repetitive negative thinking.

Conclusions:

High-volume CCT may enhance cognitive functioning beyond typical training durations.
CCT effectively reduces depressive symptoms, but its influence on emotion regulation warrants further research.
Investigating the temporal dynamics of CCT effects is crucial for understanding its mechanisms.