Search

Search

Home
...
Research Domains Indigenous Studies Pacific Peoples Environmental Knowledges Pacific Peoples fisheries and customary fisheries
Spatial variations in per- and polyfluoroalkyl substance concentrations in pooled sera from inland, coastal, and island populations

Spatial variations in per- and polyfluoroalkyl substance concentrations in pooled sera from inland, coastal, and island populations

Julia J Orr ¹, Leisa-Maree Toms ², Peter Hobson ³, Carl Kennedy ³, Daman Langguth ³, Nathaniel Kucharski ², Adriana Santivanez Olazo ¹, Jochen F Mueller ¹, Sandra Nilsson ¹

Julia J Orr ¹, Leisa-Maree Toms ², Peter Hobson ³

¹The University of Queensland, Queensland Alliance for Environmental Health Sciences, Woolloongabba, QLD, Australia.
²School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Kelvin Grove, QLD, Australia.
³Sullivan Nicolaides Pathology, Bowen Hills, QLD, Australia.

⁰The University of Queensland, Queensland Alliance for Environmental Health Sciences, Woolloongabba, QLD, Australia.

Environmental Research +

|

November 29, 2024

Related Experiment Videos

These videos have been matched automatically. Contact us if they are not relevant.

Investigating Long-Distance Transport of Perfluoroalkyl Acids in Wheat <em data-lazy-src=

Investigating Long-Distance Transport of Perfluoroalkyl Acids in Wheat via a Split-Root Exposure Technique

Published on: September 28, 2022

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

See all related videos

View abstract on PubMed

Summary

This summary is machine-generated.

Higher serum levels of certain per- and polyfluoroalkyl substances (PFAS) were found in Australian island and coastal populations compared to inland residents. This suggests geographical location influences exposure to these persistent chemicals.

Area Of Science

Environmental Chemistry
Toxicology
Public Health

Background

Per- and polyfluoroalkyl substances (PFAS) are widespread, persistent, and bioaccumulative chemicals.
Dietary intake, particularly seafood consumption, is a primary human exposure route for PFAS.
Coastal proximity may alter dietary habits and increase exposure to geographically specific PFAS sources like sea spray aerosols.

Purpose Of The Study

To investigate spatial variations in serum PFAS concentrations.
To compare PFAS levels in Australian coastal and island populations versus inland populations.
To assess the feasibility of using pooled serum samples for geographical exposure trend analysis.

Main Methods

Human serum samples were deidentified and pooled by geographical location, sex, and age group.
PFAS concentrations were analyzed using High-Performance Liquid Chromatography-Mass Spectrometry (HP LC-MS).
Quantification of 13 out of 45 targeted PFAS compounds was achieved.

Main Results

Significant spatial trends were observed in males aged ≥45 years.
Serum concentrations of PFOS, PFBA, PFDA, and PFHpS were 32-77% higher in island locations compared to inland.
A similar trend for PFHpS was noted in coastal locations.

Conclusions

Geographical location, particularly island and coastal residency, is associated with higher serum PFAS concentrations in certain demographics.
The study demonstrates the utility of pooled samples for evaluating spatial variations in human exposure to PFAS.
Further research is needed to elucidate specific exposure pathways driving these observed trends.

Keywords:

Australia Human biomonitoring Ocean proximity Pooled sera Serum PFAS concentrations Spatial comparison

Related Experiment Videos

These videos have been matched automatically. Contact us if they are not relevant.

Investigating Long-Distance Transport of Perfluoroalkyl Acids in Wheat <em>via</em> a Split-Root Exposure Technique

Investigating Long-Distance Transport of Perfluoroalkyl Acids in Wheat via a Split-Root Exposure Technique

Published on: September 28, 2022

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

See all related videos

Share

X
Facebook
LinkedIn
YouTube

ABOUT JoVE

Overview
Leadership
Blog
JoVE Help Center

AUTHORS

Publishing Process
Editorial Board
Scope & Policies
Peer Review
FAQ
Submit

LIBRARIANS

Testimonials
Subscriptions
Access
Resources
Library Advisory Board
FAQ

RESEARCH

JoVE Journal
Methods Collections
JoVE Encyclopedia of Experiments
Archive

EDUCATION

JoVE Core
JoVE Business
JoVE Science Education
JoVE Lab Manual
Faculty Resource Center
Faculty Site

Terms & Conditions of Use
Privacy Policy
Policies