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Fungal nasal polyposis - A rare case report
Jaishma Rajni Jeyaraaj1, Latha Ragunathan1, Kavitha Kanniyan1
1Department of Microbiology, Aarupadai Veedu Medical College and Hospital, Vinayaka Missions Research Foundation (Deemed to be University), Kirumampakkam, Puducherry, 607403, India.
Abstract:
Aspergillus peyronelii is an emerging and rare pathogen causing chronic rhinosinusitis with fungal nasal polyposis among immunocompetent individuals. Usual fungal aetiologies are Aspergillus spp, Mucor spp and Cladosporium spp, among which Aspergillus flavus being the most common in India. We present a case of 28-year-old woman with unilateral nasal obstruction with 15 years history of allergy, diagnosed as nasal polyposis, uncovered an uncommon pathogen A.peyronelii. Being a saprophytic and endophytic fungus, meticulously diagnostic approaches were employed for the precise identification. Further researches are needed to optimize diagnostic strategies and therapeutic intervention of this species.
Insights
Aspergillus peyronelii is a rare fungus causing chronic rhinosinusitis with fungal nasal polyposis in immunocompetent patients. This case highlights the need for advanced diagnostics to identify uncommon fungal pathogens like A. peyronelii.
Area of Science:
- Mycology
- Infectious Diseases
- Otolaryngology
Background:
- Chronic rhinosinusitis with fungal nasal polyposis (CRSwNP) is often caused by common fungi like Aspergillus flavus, particularly in India.
- Immunocompetent individuals can develop CRSwNP, necessitating a broader differential diagnosis beyond typical pathogens.
Observation:
- A 28-year-old woman presented with unilateral nasal obstruction and a 15-year history of allergies, diagnosed with nasal polyposis.
- Diagnostic evaluation revealed an uncommon fungal pathogen, Aspergillus peyronelii, as the causative agent.
Findings:
- Aspergillus peyronelii, a saprophytic and endophytic fungus, was precisely identified through meticulous diagnostic approaches.
- This case represents a rare instance of A. peyronelii causing CRSwNP in an immunocompetent host.
Implications:
- The identification of A. peyronelii underscores the importance of considering rare fungal pathogens in CRSwNP cases.
- Further research is crucial to optimize diagnostic strategies and therapeutic interventions for A. peyronelii infections.
- This finding expands the known spectrum of fungal etiologies for CRSwNP in immunocompetent individuals.
