Insular Epilepsy: Functions, Diagnostic Approaches, and Surgical Interventions

Epilepsy, a chronic neurological disorder characterized by recurrent seizures, affects a significant portion of the global population, with drug-resistant epilepsy (DRE) presenting a major treatment challenge. Insular epilepsy, originating from this complex region, exhibits a broad range of symptoms, making diagnosis particularly difficult. Advanced imaging techniques and invasive procedures like stereoelectroencephalography (SEEG) are often crucial for accurately localizing the epileptogenic zone. Surgical resection remains the primary treatment for DRE, with recent advancements in microsurgical techniques and neuroimaging improving outcomes. Additionally, minimally invasive approaches like laser interstitial thermal therapy (LITT) and radiofrequency thermocoagulation (RFTC) offer promising alternatives.