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Comparing effectiveness of 3-needle approach versus 5-needle approach of genicular nerve block on pain and quality of life in chronic osteoarthritis of knee: a double blinded randomised controlled trial

  • 0Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences [AIIMS], Jodhpur, Rajasthan, India. meghabhargava@outlook.in.
Bmc Musculoskeletal Disorders +

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November 29, 2024

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November 29, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

A 3-point versus 5-point genicular nerve block (GNB) approach for knee osteoarthritis showed similar pain reduction. However, the 5-point GNB approach resulted in superior quality of life improvements after three months.

Area Of Science

  • Pain Management
  • Musculoskeletal Disorders
  • Interventional Pain Procedures

Background

  • Knee osteoarthritis (KOA) is a degenerative joint disease causing pain and functional decline.
  • Genicular Nerve Blocks (GNB) and Radiofrequency Ablation (GNRFA) are interventions for KOA pain.
  • Research is ongoing to identify precise anatomical targets for improved GNB efficacy.

Purpose Of The Study

  • To compare the effectiveness of ultrasound-guided 3-point versus 5-point genicular nerve block (GNB) approaches.
  • To evaluate the impact on pain and quality of life in patients with chronic knee osteoarthritis (KOA).

Main Methods

  • A double-blind, randomized controlled trial was conducted.
  • 180 patients with KOA were randomized into 3-point or 5-point GNB groups.
  • Pain (NRS), functional status (TUG test), and quality of life (QoL-KOOS) were assessed at baseline, 1, and 3 months.

Main Results

  • Both 3-point and 5-point GNB approaches reduced pain and improved TUG test duration at 1 and 3 months.
  • No significant difference in pain reduction or functional improvement was observed between the two groups.
  • The 5-point GNB group reported significantly higher quality of life improvements at 3 months (p=0.011).

Conclusions

  • Neither the 3-point nor the 5-point GNB approach was definitively superior for pain reduction in KOA.
  • The 5-point GNB technique demonstrated a statistically significant advantage in improving quality of life at three months post-procedure.
  • The enhanced spread of injectate in the 5-point approach may explain the improved quality of life outcomes.

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