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  1. Home
  3. Exploring The Antiquity Of Rheumatoid Arthritis: A Case Study From Medieval Transylvania.
  1. Home
  3. Exploring The Antiquity Of Rheumatoid Arthritis: A Case Study From Medieval Transylvania.

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Exploring the antiquity of rheumatoid arthritis: A case study from medieval Transylvania.

Megan A Heron1, Joseph Z Forstot2, Zsolt Nyárádi3

  • 1Department of Anthropology, Florida Atlantic University, FL, USA.

International Journal of Paleopathology
|November 30, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Rheumatoid arthritis (RA) lesions were identified on a medieval skeleton from Transylvania, suggesting the condition existed in Europe before the 15th century. This finding challenges theories of RA

Keywords:
Hungarian culturePaleorheumatologyPolyarthropathyRomania

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Area of Science:

  • Paleopathology
  • Medieval Archaeology
  • Rheumatology

Background:

  • The antiquity and geographical origin of rheumatoid arthritis (RA) are debated among researchers.
  • Some theories propose RA originated in the Americas and was introduced to Europe post-15th century.
  • This study investigates skeletal evidence to address these debates.

Purpose of the Study:

  • To evaluate erosive pathological lesions on a medieval Transylvanian skeleton.
  • To determine if these lesions are indicative of rheumatoid arthritis.
  • To contribute to understanding the historical prevalence of RA.

Main Methods:

  • Macroscopic and radiographic examination of skeletal remains.
  • Radiocarbon dating of the skeleton to Cal 1300 CE - 1415 CE.
  • Differential diagnosis following established paleopathological protocols.

Main Results:

  • Periarticular erosive lesions were observed on multiple synovial joints, including small joints of hands and feet.
  • The skeletal remains belonged to a probable adult female.
  • Lesions were characteristic of rheumatoid arthritis.

Conclusions:

  • The identified lesions are indicative of rheumatoid arthritis predating the mid-15th century.
  • This finding supports the presence of RA in medieval Europe prior to European colonization of the Americas.
  • The study highlights the need for further research into RA's historical distribution.