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Related Experiment Videos

[Apathetic form of thyrotoxicosis].

G S Zefirova, V V Lebedev, G G Mirzoiants

    Terapevticheskii Arkhiv
    |January 1, 1986
    PubMed
    Summary

    Apathetic thyrotoxicosis presents without typical symptoms, featuring ptosis, heart issues, and myopathy. Treatment, including surgery or mercazolyl, resolved these clinical signs.

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    Area of Science:

    • Endocrinology
    • Neurology

    Background:

    • Thyrotoxicosis, or hyperthyroidism, typically presents with overt symptoms like weight loss and tremors.
    • The apathetic form of thyrotoxicosis is less common, particularly in older individuals, and may present atypically.

    Observation:

    • Two cases of apathetic thyrotoxicosis in women (39 and 54 years old) are presented.
    • Key clinical features included ptosis, cardiovascular disorders, and thyrotoxic myopathy.
    • Electromyography (EMG) confirmed thyrotoxic myopathy.

    Findings:

    • The absence of classic thyrotoxicosis symptoms was noted.
    • Surgical therapy and chemotherapy with mercazolyl led to the resolution of clinical symptoms.
    • EMG findings corroborated the diagnosis of thyrotoxic myopathy.

    Implications:

    • Highlights the importance of considering atypical presentations of thyrotoxicosis.
    • Suggests that prompt diagnosis and treatment can effectively manage even subtle forms of hyperthyroidism.
    • Underscores the utility of EMG in diagnosing thyrotoxic myopathy.

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