Antibiotic resistance partitioning during on-farm manure separation and high temperature rotary drum composting
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View abstract on PubMed
Summary
This summary is machine-generated.Manure management strategies impact antibiotic resistance. Solid-liquid separation leaves most antibiotic resistance factors untreated in liquid manure, while composting effectively removes bacteria but not all genes or antibiotic residues.
Area Of Science
- Environmental Science
- Agricultural Microbiology
- Veterinary Public Health
Background
- Manure application as fertilizer poses environmental risks by transmitting antibiotics, antibiotic-resistant bacteria (ARB), and antibiotic-resistant genes (ARGs) to ecosystems.
- Limited understanding exists on the fate of specific antibiotics and ARGs within different manure fractions during on-farm management.
Purpose Of The Study
- To conduct a mass flow analysis of antibiotic resistance factors (antibiotics, ARGs, ARB) through solid-liquid separation and subsequent bedding recovery unit (BRU) composting.
- To determine the efficacy of on-farm manure management processes in reducing environmental exposure risks associated with antibiotic resistance.
Main Methods
- Solid-liquid separation of manure to partition antibiotic resistance factors.
- High-temperature rotary composting of the solid fraction in a bedding recovery unit (BRU).
- Mass flow analysis tracking antibiotics, ARB, and ARGs through the management processes.
Main Results
- Solid-liquid separation resulted in 95% of the mass, including most antibiotic resistance factors, remaining in the liquid fraction destined for lagoon storage.
- Composting in the BRU effectively removed 100% of ARB and significantly reduced five of eight ARGs (>95%), but antibiotic residuals remained largely untreated.
- Tetracyclines and tulathromycin sorbed to solids, while beta-lactams were found only in the liquid fraction; some ARGs persisted post-composting.
Conclusions
- On-farm manure management, particularly solid-liquid separation, leaves a significant portion of antibiotic resistance factors untreated in liquid manure.
- BRU composting effectively eliminates ARB and reduces many ARGs but is less effective for antibiotic residuals and certain ARGs, highlighting the need for a mass balance approach.
- Understanding the mass flow of antibiotic resistance factors is crucial for assessing and mitigating environmental risks associated with manure management.
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