Evaluation of Acoustic Voice Quality Index in Persian-Speaking Parkinson's Patients Compared to Healthy Controls and Its Association With Disease Severity Based on UPDRS-III and Dysarthria Severity

  • 0Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Summary

This summary is machine-generated.

The Acoustic Voice Quality Index (AVQI) effectively identifies voice disorders in Persian Parkinson's patients with dysarthria. Higher AVQI scores correlate with increased disease and dysarthria severity, indicating its potential as a diagnostic tool.

Area Of Science

  • Neurology
  • Speech-Language Pathology
  • Biomedical Engineering

Background

  • Parkinson's disease frequently causes dysarthria, impacting speech subsystems like phonation.
  • The Acoustic Voice Quality Index (AVQI) shows promise in predicting Parkinson's disease onset and severity.

Purpose Of The Study

  • To investigate the AVQI in Persian-speaking Parkinson's patients with hypokinetic dysarthria compared to healthy controls.
  • To assess the association between AVQI and disease severity (UPDRS-III) and dysarthria severity.

Main Methods

  • An epidemiological study involving 30 Parkinson's patients with hypokinetic dysarthria and 30 healthy controls.
  • Disease severity assessed using Unified Parkinson's Disease Rating Scale-Part III (UPDRS-III).
  • Speech samples recorded for AVQI extraction using Praat software.

Main Results

  • The AVQI was significantly higher in Parkinson's patients than in controls (P ≤ 0.001).
  • A significant positive correlation was found between AVQI and both UPDRS-III scores (P ≤ 0.001) and dysarthria severity (P ≤ 0.001).

Conclusions

  • AVQI can distinguish voice disorders in Persian-speaking Parkinson's patients with hypokinetic dysarthria.
  • AVQI positively correlates with Parkinson's disease and dysarthria severity in this population.
  • Further research is recommended to explore this correlation in other languages.