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Osteoporosis and Rheumatoid Arthritis: A Review of Current Understanding and Practice
Fiona Kirkham-Wilson1,2, Elaine Dennison1
1MRC Lifecourse Epidemiology Centre, University Hospitals Southampton, Southampton, UK.
Abstract:
This review presents a current perspective on the association between rheumatoid arthritis (RA) and osteoporosis. Many factors contribute to the increased risk of osteoporosis and fracture in RA patients. These factors include advanced age, duration of disease, long-term glucocorticoid use, and poor inflammation control inflammation in RA. This review discusses current guidelines and their limitations in assessing bone health in RA-related osteoporosis. Available anti-osteoporotic treatments, their mechanisms of action, and their potential benefits in managing the interaction between RA and osteoporosis are discussed. We also consider potential advancements, including areas of future development in RA and osteoporosis diagnosis and management.
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