Comparison of Four Scoring Systems for Patients With Nonvariceal Upper Gastrointestinal Bleeding

Elrasheed M Elsabani1, Badr A Badr2, Mohammad Dhalaan3

  • 1Hospital Medicine, Johns Hopkins Aramco Healthcare, Dhahran, SAU.

Cureus
|December 2, 2024
PubMed

Insights

This study compared risk scores for upper gastrointestinal bleeding (UGIB). The Glasgow-Blatchford score (GBS) best predicted transfusions, while the National Early Warning Score (NEWS) predicted admissions and mortality.

Area of Science:

  • Gastroenterology
  • Critical Care Medicine
  • Health Services Research

Background:

  • Upper gastrointestinal bleeding (UGIB) is a significant cause of mortality and morbidity.
  • Accurate risk stratification is essential for managing UGIB patients and allocating resources effectively.
  • Existing risk assessment tools, including Glasgow-Blatchford score (GBS), AIMS65, National Early Warning Score (NEWS), and NEWS + Lactate (NEWS+L), have varying strengths and limitations.

Purpose of the Study:

  • To evaluate and compare the predictive performance of GBS, AIMS65, NEWS, and NEWS+L for critical outcomes in nonvariceal upper GI bleeding (NVUGIB).
  • To assess the accuracy of these scores in predicting the need for blood transfusion, inpatient admission, and 90-day mortality.

Main Methods:

  • A retrospective review of 229 patients with NVUGIB was conducted.
  • Demographic data, clinical presentation, laboratory values, and vital signs were collected.
  • GBS, AIMS65, NEWS, and NEWS+L scores were calculated for each patient, and their predictive accuracy was assessed using receiver operating characteristic curves (AUCs).

Main Results:

  • The Glasgow-Blatchford score (GBS) demonstrated the highest predictive accuracy for blood transfusion (AUC: 75.7%).
  • The National Early Warning Score (NEWS) was the best predictor for inpatient admission (AUC: 84.04%).
  • For 90-day mortality, NEWS and NEWS+L showed similar predictive performance (AUCs: 77.25% and 77.52%, respectively), outperforming GBS and AIMS65.

Conclusions:

  • Each risk score possesses distinct predictive capabilities for specific outcomes in NVUGIB.
  • GBS is most accurate for predicting transfusion needs, NEWS for admission, and NEWS/NEWS+L for mortality.
  • Combining these scores may enhance risk stratification and guide targeted therapies, ultimately improving patient outcomes in UGIB.

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