Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intentional Oversizing of Valve in Transcatheter Aortic Valve Replacement: Is Bigger Better? A Large, Single-Center Experience.

Structural heart : the journal of the Heart Team·2024
Same author

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.

Cell stem cell·2022
Same author

Enhanced Detection of Heart Valve Disease Using Integrated Artificial Intelligence at Scale.

The Annals of thoracic surgery·2021
Same author

Early clinical and procedural outcomes in large series of 34-mm self-expanding transcatheter aortic valve replacement.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2019
Same author

Durability and Clinical Outcomes of Transcatheter Aortic Valve Replacement for Failed Surgical Bioprostheses.

Circulation. Cardiovascular interventions·2019
Same author

Clinical impact of baseline chronic kidney disease in patients undergoing transcatheter or surgical aortic valve replacement.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2018

Related Experiment Video

Updated: Jun 6, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.0K

Surgical Aortic Valve Replacement Using a Supra-Annular Self-Expanding Bioprosthesis.

Daniel P O'Hair1, Srinivas Iyengar1, Molly G Ware1

  • 1Cardiovascular Services, Boulder Community Health, Boulder, Colorado, USA.

JACC. Case Reports
|December 2, 2024
PubMed
Summary

Surgically implanting a self-expanding supra-annular valve, typically used for transcatheter aortic valve replacement (TAVR), offers excellent hemodynamic outcomes. This approach can be a viable option for patients unsuitable for TAVR procedures.

Keywords:
aortic stenosisself-expandingsupra-annularsurgical aortic valve replacementtranscatheter aortic valves

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

2.8K

Related Experiment Videos

Last Updated: Jun 6, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

14.0K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.3K
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

2.8K

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Biomaterials Science

Background:

  • Transcatheter aortic valve replacement (TAVR) with self-expanding supra-annular valves demonstrates superior hemodynamic performance and durability compared to surgical aortic valve replacement (SAVR).
  • Investigating the feasibility of surgically implanting TAVR valves aims to combine the benefits of these advanced valves with a surgical approach.

Observation:

  • A self-expanding supra-annular valve (Evolut, Medtronic) was surgically implanted in four patients undergoing SAVR using standard surgical techniques.
  • Patient profiles included three with native aortic valve disease and one with a degenerated bioprosthesis.
  • Valve sizes implanted were 29-mm Evolut valves, with measured native annulus sizes of 21-mm (n=3) and 23-mm (n=1).

Findings:

  • Successful surgical implantation of the Evolut valve was achieved in all four patients without observed valve migration.
  • Post-procedure, no patients required a pacemaker, and echocardiography revealed low mean aortic valve gradients (5.3 mm Hg).
  • One patient experienced a mild paravalvular leak, indicating a generally safe and effective procedure.

Implications:

  • Surgical aortic valve replacement using a transcatheter self-expanding supra-annular valve is a feasible alternative for patients ineligible for TAVR.
  • This technique may offer improved hemodynamic outcomes and valve durability in specific patient populations.
  • Further research is warranted to establish long-term outcomes and expand the application of this hybrid approach.