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Factor XIII Deficiency Presenting With Duodenal Hematoma in a 3-Year-Old Female: A Comprehensive Radiological

Muhammad Khubaib Ullah1, Faheemullah Khan2, Muhammad Aman3

  • 1Ayub Medical College Abbottabad Pakistan.

Clinical Case Reports
|December 2, 2024
PubMed

Insights

Factor XIII (FXIII) deficiency in children often causes bleeding issues. This case highlights an unusual presentation of FXIII deficiency in a young girl with abdominal pain and vomiting, managed conservatively.

Area of Science:

  • Pediatric Hematology
  • Rare Bleeding Disorders

Background:

  • Factor XIII (FXIII) deficiency is a rare inherited bleeding disorder.
  • Typical pediatric presentations include umbilical stump bleeding, soft tissue hemorrhage, and poor wound healing.
  • Atypical presentations can pose diagnostic challenges.

Purpose of the Study:

  • To report an atypical presentation of FXIII deficiency in a pediatric patient.
  • To emphasize the importance of considering rare bleeding disorders in children with non-specific symptoms.

Main Methods:

  • Case report of a 3-year-old female presenting with abdominal pain and vomiting.
  • Clinical evaluation and management by the pediatric surgery team.
  • Review of typical and atypical FXIII deficiency presentations.

Main Results:

  • The patient presented with symptoms not commonly associated with FXIII deficiency.
  • Conservative management was initiated by the pediatric surgery team.
  • This case underscores the variability in FXIII deficiency manifestation.

Conclusions:

  • FXIII deficiency can manifest atypically in children, presenting with gastrointestinal symptoms.
  • Early recognition and appropriate management are crucial for favorable outcomes.
  • This case broadens the understanding of FXIII deficiency's clinical spectrum in pediatrics.

Keywords:
abdominal painduodenal hematomafactor XIII deficiencynon‐surgical managementpediatric caseradiological assessment

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