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Related Experiment Video

Updated: Jun 25, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

A microscale soft lithium-ion battery for tissue stimulation.

Yujia Zhang^1,2, Tianyi Sun³, Xingyun Yang¹

¹Department of Chemistry, University of Oxford, Oxford, UK.

Nature Chemical Engineering

|December 2, 2024

Summary

This summary is machine-generated.

Researchers developed a microscale soft flexible lithium-ion droplet battery (LiDB) using silk hydrogel. This biocompatible and rechargeable power source enables new possibilities for minimally invasive biomedical devices.

Keywords:

Batteries Biomedical engineering Gels and hydrogels

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Area of Science:

Biomedical Engineering
Materials Science
Energy Storage

Background:

Miniaturization of biomedical devices requires smaller, soft power sources.
Previous droplet-based power sources lacked rechargeability.
Soft, biocompatible batteries are crucial for minimally invasive applications.

Purpose of the Study:

To develop a microscale, soft, flexible, and rechargeable battery for biomedical applications.
To demonstrate the capabilities and applications of the novel droplet battery.

Main Methods:

Fabrication of a lithium-ion droplet battery (LiDB) using a biocompatible silk hydrogel.
Lipid-supported assembly of droplets for battery construction.
Integration of magnetic particles for mobile energy courier functionality.

Main Results:

Demonstrated a high-capacity, rechargeable microscale soft flexible lithium-ion droplet battery (LiDB).
Showcased triggerable activation, biocompatibility, and biodegradability.
Successfully powered synthetic cell experiments and ex vivo heart functions.

Conclusions:

The developed LiDB is a versatile, tiny power source for advanced biomedical applications.
The LiDB's unique properties enable its use in mobile energy delivery and device operation.
This innovation paves the way for next-generation minimally invasive medical technologies.