Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Salmonella osteomyelitis in a rhesus monkey.

S A Klumpp, D S Weaver, C P Jerome

    Veterinary Pathology
    |March 1, 1986
    PubMed
    Summary

    A rhesus monkey developed severe Salmonella-induced osteomyelitis and enteritis. The infection led to bone lesions and systemic illness, indicating poor resistance possibly due to anemia or toxic exposure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Immunohistochemical Characterization of Sarcomas in Trp53+/- Haploinsufficient Mice.

    Toxicologic pathology·2017
    Same author

    Environmental pathobiology and global opportunities.

    Veterinary pathology·2013
    Same author

    Ovarian pathology in rhesus macaques: a 12-year retrospective.

    Journal of medical primatology·2010
    Same author

    Treatment with a potent cathepsin K inhibitor preserves cortical and trabecular bone mass in ovariectomized monkeys.

    Calcified tissue international·2009
    Same author

    Rhesus lymphocryptovirus type 1-associated B-cell nasal lymphoma in SIV-infected rhesus macaques.

    Veterinary pathology·2008
    Same author

    Trichomonad gastritis in rhesus macaques (Macaca mulatta) infected with simian immunodeficiency virus.

    Veterinary pathology·2005

    Area of Science:

    • Veterinary Pathology
    • Primate Medicine
    • Infectious Diseases

    Background:

    • Osteomyelitis is a serious bone infection that can affect various species.
    • Salmonella infections can lead to severe systemic complications in non-human primates.
    • Rhesus monkeys are common models for studying infectious diseases and their systemic effects.

    Observation:

    • An adult male rhesus monkey presented with clinical signs of severe osteomyelitis in the left femur.
    • Salmonella species were isolated from fecal samples, blood, and bone lesions.
    • The animal exhibited poor response to antibiotic treatment, leading to euthanasia.

    Findings:

    • Microscopic examination revealed severe osteomyelitis with pathologic fracture and involucrum, primarily affecting the left femur, right femur, tibia, and fibula.
    • Additional findings included hepatic microgranulomas, tubulointerstitial nephritis, lymphadenopathy with histiocytosis and erythrophagocytosis, and mild colitis.
    • Serum electrophoresis suggested compromised immune status, potentially linked to anemia or polychlorinated biphenyl toxicosis.

    Implications:

    • This case highlights the potential for Salmonella to cause severe osteomyelitis in rhesus monkeys.
    • The findings suggest that underlying conditions like anemia or toxicosis may lower resistance to systemic Salmonella infections.
    • Understanding these factors is crucial for diagnosing and managing similar cases in non-human primates and for interpreting disease models.

    Related Experiment Videos