Continuous Glucose Monitor Accuracy for Diabetes Management in Hospitalized Children.

Area of Science:

• Pediatric Endocrinology
• Medical Device Technology
• Diabetes Management

Background:

• Continuous glucose monitors (CGMs) adoption in pediatric inpatient settings is limited due to insufficient data on their reliability.
• Assessing CGM accuracy in hospitalized children is crucial for clinical decision-making.

Purpose of the Study:

• To evaluate the accuracy and clinical reliability of the Dexcom G6 CGM system in pediatric patients admitted to a hospital.
• To provide data supporting the integration of CGMs into inpatient pediatric diabetes care.

Main Methods:

• Retrospective review of Dexcom G6 CGM data and point-of-care (POC) glucose values from pediatric patients (ages 2-18).
• Analysis included Mean Absolute Relative Difference (MARD) and Clarke Error Grid (CEG) analysis.
• Investigated the impact of serum pH, sodium, and blood urea nitrogen (BUN) on CGM accuracy.

Main Results:

• The Dexcom G6 system demonstrated a Mean Absolute Relative Difference (MARD) of 15.9% in 2,904 paired CGM and POC measurements.
• 96.6% of CGM values fell within clinically acceptable zones (A and B) on the Clarke Error Grid.
• CGM accuracy was not significantly impacted by serum pH, sodium, or BUN levels.

Conclusions:

• The Dexcom G6 CGM system shows acceptable accuracy for monitoring glucose levels in hospitalized children with diabetes.
• Integrating CGM data into electronic health records can enhance diabetes management for pediatric inpatients.
• Further adoption of CGMs in pediatric hospital settings is warranted based on demonstrated reliability.