Related Experiment Video

Updated: Jun 6, 2025

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

18.8K

Continuous Glucose Monitor Accuracy for Diabetes Management in Hospitalized Children

Neha Garg1, Kamryn Lewis1, Perrin C White1

  • 1Division of Pediatric Endocrinology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.

Diabetes Care
|December 2, 2024
PubMed

Insights

Continuous glucose monitors (CGMs) are accurate for hospitalized children with diabetes. Integrating CGM data into electronic health records can improve patient management and care.

Area of Science:

  • Pediatric Endocrinology
  • Medical Device Technology
  • Diabetes Management

Background:

  • Continuous glucose monitors (CGMs) adoption in pediatric inpatient settings is limited due to insufficient data on their reliability.
  • Assessing CGM accuracy in hospitalized children is crucial for clinical decision-making.

Purpose of the Study:

  • To evaluate the accuracy and clinical reliability of the Dexcom G6 CGM system in pediatric patients admitted to a hospital.
  • To provide data supporting the integration of CGMs into inpatient pediatric diabetes care.

Main Methods:

  • Retrospective review of Dexcom G6 CGM data and point-of-care (POC) glucose values from pediatric patients (ages 2-18).
  • Analysis included Mean Absolute Relative Difference (MARD) and Clarke Error Grid (CEG) analysis.
  • Investigated the impact of serum pH, sodium, and blood urea nitrogen (BUN) on CGM accuracy.

Main Results:

  • The Dexcom G6 system demonstrated a Mean Absolute Relative Difference (MARD) of 15.9% in 2,904 paired CGM and POC measurements.
  • 96.6% of CGM values fell within clinically acceptable zones (A and B) on the Clarke Error Grid.
  • CGM accuracy was not significantly impacted by serum pH, sodium, or BUN levels.

Conclusions:

  • The Dexcom G6 CGM system shows acceptable accuracy for monitoring glucose levels in hospitalized children with diabetes.
  • Integrating CGM data into electronic health records can enhance diabetes management for pediatric inpatients.
  • Further adoption of CGMs in pediatric hospital settings is warranted based on demonstrated reliability.
Abstract

More Related Videos

Simple Continuous Glucose Monitoring in Freely Moving Mice03:25

Simple Continuous Glucose Monitoring in Freely Moving Mice

Published on: February 24, 2023

5.2K
Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing06:55

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing

Published on: May 8, 2021

5.5K

Related Concept Videos

Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
152
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
504
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
235
Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
1.4K
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
145