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Novel Injectable Nerve Stimulation Electrode Placed on the Dorsal Root Ganglion Using an Extravertebral Approach: A
Bart Billet1, Christian Jessen2, Bernhard Moriggl3
1Pain Clinic, AZ Delta, Roeselare, Belgium; RESEARCH Stimulus Group, Vrije Universiteit Brussel, Brussels, Belgium.
Pain Physician
|December 2, 2024
Summary
A new injectable electrode system for dorsal root ganglion stimulation (DRGS) demonstrated accurate placement near lumbar DRGs in a cadaver study. This technique shows potential as a less invasive and more accessible alternative to current DRGS methods.
Area of Science:
- Neurosurgery
- Pain Management
- Medical Device Technology
Background:
- Dorsal root ganglion stimulation (DRGS) treats severe pain but faces challenges with cost, specialized training, and technical requirements.
- Current DRGS systems are expensive and complex, limiting patient access and clinical applicability.
Purpose of the Study:
- To evaluate the feasibility of a novel, rapidly deliverable, injectable electrode for near-DRG stimulation.
- To assess a fluoroscopy-guided transforaminal approach for placing these electrodes in human cadavers.
Main Methods:
- A feasibility study was conducted in a cadaver laboratory setting.
- Three pain physicians trained on the injectable electrode system performed implantations in two adult male cadavers.
- Electrodes were placed near lumbar L1 and L2 DRGs, with anatomical dissection for verification.
Main Results:
- Injectable electrodes were accurately positioned within 1 mm of the target DRGs at L1 and L2 levels.
- The benchmark DRGS device also showed precise placement within 1 mm of the L1 DRG.
Conclusions:
- This cadaver study is the first to assess a transforaminal approach for injectable DRG electrodes.
- The promising accuracy and efficiency suggest this method could be a viable alternative to existing DRGS techniques.
- Further clinical investigation is warranted to explore the potential of this new DRGS approach.

