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Multi-analyte Biochip MAB Based on All-solid-state Ion-selective Electrodes ASSISE for Physiological Research

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Published on: April 18, 2013

Leading edge biosensing applications based on AIE technology.

Weitao Zhu¹, Jiaao Wang¹, Kaixin Lei¹

¹Clinical Medicine (Eight-Year Program), West China School of Medicine, Sichuan University, Chengdu, 610044, China.

Biosensors & Bioelectronics

|December 2, 2024

Summary

This summary is machine-generated.

Aggregation-induced emission (AIE) overcomes limitations in traditional luminescent probes, enabling sensitive detection in biological imaging. This review explores AIE

Keywords:

AIE Bioimaging Biosensing Detection

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Area of Science:

Materials Science
Biotechnology
Chemical Sensing

Background:

Luminescent materials are crucial for biological imaging, but conventional probes face limitations like aggregation-induced quenching (ACQ).
ACQ significantly restricts the sensitivity and selectivity of luminescent materials in biological and chemical sensing applications.
Existing luminescent materials struggle with analyte detection in complex biological environments due to aggregation issues.

Purpose of the Study:

To review the fundamental working principles of aggregation-induced emission (AIE) technology.
To explore the core mechanisms driving AIE and its potential for innovation.
To present cutting-edge biosensing applications of AIE in various detection fields.

Main Methods:

Review of the theoretical framework and working principles of AIE.
Analysis of research advancements in AIE materials and mechanisms.
Compilation of current AIE-based biosensing applications.

Main Results:

AIE provides a robust solution to the ACQ problem, enhancing luminescent probe performance.
Understanding AIE mechanisms is key to developing advanced AIE-based technologies.
AIE technology demonstrates significant potential across substance, biological, and disease detection.

Conclusions:

Aggregation-induced emission (AIE) offers a breakthrough for luminescent materials in biosensing.
Further research into AIE mechanisms will drive innovation in practical applications.
AIE technology is poised for significant future development in biological imaging and diagnostics.