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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Irish Prostate Cancer Outcomes Research (IPCOR) registry: cohort profile.

Noa Gordon1, Cara Dooley2, Áine Murphy2

  • 1UCD School of Medicine and UCD Conway Institute, University College Dublin, Dublin, Ireland noa.gordon1@ucd.ie.

BMJ Open
|December 2, 2024
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Summary

The Irish Prostate Cancer Outcomes Research (IPCOR) registry collected data on over 6,800 men, revealing early-stage diagnoses through opportunistic PSA screening. This resource aims to improve prostate cancer care in Ireland and globally.

Keywords:
IrelandProstatic NeoplasmsREGISTRIES

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Area of Science:

  • Oncology
  • Epidemiology
  • Clinical Research

Background:

  • The Irish Prostate Cancer Outcomes Research (IPCOR) registry was established in 2015.
  • It is a large-scale, prospective cohort study designed to improve prostate cancer care for men in Ireland.

Purpose of the Study:

  • To describe the IPCOR registry and its data collection methods.
  • To inform and enhance the prostate cancer journey for men in Ireland.

Main Methods:

  • Prospective cohort study conducted from 2016 to 2020.
  • Data collected from 6,816 newly diagnosed prostate cancer patients across 16 Irish hospitals.
  • Comprehensive clinical data including diagnosis, treatments, and follow-up, plus patient-reported outcomes from 873 men.

Main Results:

  • High incidence of prostate cancer diagnosis via opportunistic Prostate-Specific Antigen (PSA) screening.
  • A significant proportion of cases were identified at an early stage.

Conclusions:

  • The IPCOR registry provides valuable insights into prostate cancer diagnosis and treatment patterns in Ireland.
  • Future plans include IPCOR 2.0, a longitudinal registry and biorepository, and continued collaboration with researchers and patients.