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Updated: Jun 6, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
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Introducing all-inkjet-printed microneedles for in-vivo biosensing.

Giulio Rosati1, Patricia Batista Deroco2,3,4, Matheus Guitti Bonando2,5,6

  • 1Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, 08193, Bellaterra, Barcelona, Spain. giulio.rosati@icn2.cat.

Scientific Reports
|December 2, 2024
PubMed
Summary

We developed a simple, scalable inkjet-printing method for fabricating conductive microneedles using silver nanoparticles. This technique enables cost-effective production for applications like plant biosensing.

Keywords:
EISInkjet printingMicroneedlesPlantsPrecision agricultureSilver nanoparticles

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biosensing

Background:

  • Microneedles are crucial for pain-free drug delivery and wearable biosensors.
  • Current microneedle fabrication is complex, expensive, and not suitable for mass production, limiting applications in fields like precision agriculture.
  • There is a need for scalable and cost-effective microneedle fabrication methods.

Purpose of the Study:

  • To introduce a novel, simple, and scalable method for fabricating conductive microneedles.
  • To demonstrate the use of inkjet printing with silver nanoparticle inks for microneedle production.
  • To showcase a potential application of these microneedles in plant electrochemical monitoring.

Main Methods:

  • Utilized an all-inkjet-printing approach for microneedle fabrication.
  • Employed silver nanoparticle-based inks for creating conductive microneedle structures.
  • Developed a proof-of-concept application for monitoring plant electrochemical properties.

Main Results:

  • Successfully fabricated scalable, conductive microneedles using inkjet printing.
  • Demonstrated the versatility of the method by using silver nanoparticle inks.
  • Showcased the feasibility of using these microneedles for plant electrochemical monitoring.

Conclusions:

  • The developed inkjet-printing method offers a simple, scalable, and cost-effective solution for conductive microneedle fabrication.
  • This technology has broad potential applications, including biosensing and precision agriculture.
  • The method is extensible to other metallic nanoparticle inks, enhancing its versatility.