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Ultrasound characteristics of alveolar soft part sarcoma in pediatric patients: a retrospective analysis
Siwei Wang1, Yu Wang1, Jiatong Xu2
1Department of Ultrasound, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No.56 Nan Li Shi Road, Xi Cheng District, Beijing, 100045, China.
Objective:
This study aims to review and summarize the ultrasound characteristics of alveolar soft part sarcoma (ASPS) in children.
Methods:
We retrospectively analyzed 20 pediatric ASPS cases confirmed by surgery or biopsy at our hospital between January 2014 and January 2024. Clinical data, including age, sex, symptoms, and tumor location, were collected. Ultrasound reports and images were reviewed to extract data on tumor size, boundaries, echogenicity, and vascularity.
Results:
The study included 20 children with ASPS. The tumors were located in the trunk and limbs (50%), as well as in the head and neck (50%). Compared with tumors in the trunk and limbs, head and neck tumors were smaller in size, had more pronounced symptoms, and had a lower incidence of metastasis. Ultrasound features predominantly included hypoechoic masses with clear boundaries, heterogeneous echogenicity, and rich internal and surrounding vascularity, often with tortuous and dilated blood vessels. Eight patients had distant metastases at diagnosis, seven of which involved the lungs. There was a moderate correlation between tumor size and the risk of distant metastasis (r = 0.64).
Conclusion:
Understanding the clinical and ultrasound characteristics of pediatric ASPS can facilitate earlier and more accurate diagnosis.
