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Updated: Jun 6, 2025

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
Published on: November 11, 2022
A Structural Equation Modelling Exploration of the Role of Schizotypal Traits, Cognitive Schemas and Dysfunctional
Robert Aidelbaum1, Shreya Jagtap1,2, Rachel Rumas1
1Department of Psychological Clinical Science, University of Toronto Scarborough, Toronto, Ontario, Canada.
Introduction:
Evidence highlights the importance of social isolation as a critical yet underserved treatment target for individuals managing psychosis. Schizotypal traits represent a useful model of psychosis, facilitating the assessment of contributors to social isolation without the confounds associated with schizophrenia. This study utilised structural equation modelling to examine the unique predictive capacity of schizotypal traits for subjective and objective indices of social isolation. In addition, the potentially mediating role of negative core schemas and dysfunctional attitudes was assessed.
Methods:
Structural equation modelling was used to measure and compare the relationships between the constructs of interest simultaneously.
Results:
Satisfactory fit indices were attained with separate models predicting loneliness and social engagement. Results support the partial mediation of the relationships between positive and negative traits, internalising symptoms and loneliness. While all three direct pathways were significant, all three were partially mediated. Of note, these mediated effects were not observed in the model predicting social engagement, with the only significant pathways being those directly from positive and negative schizotypal traits.
Conclusions:
Schizotypal traits directly predict loneliness and social engagement above that accounted for by internalising symptoms. Cognitive factors partially mediate the relationships between schizotypy and loneliness but not the size of an individual's social network. Cognitive interventions may be well suited for reducing loneliness; however, other approaches may be required to increase social networks for individuals with high levels of schizotypy.
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