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Related Concept Videos

Peroxisomes01:24

Peroxisomes

Peroxisomes are specialized organelles present in fungi, plant, and animal cells. It can vary in number, size, morphology, and activity depending on the type of tissue and the nutritional state of the cell. For example, cells with active lipid metabolism, such as adipocytes, neurons, and hepatocytes, have more peroxisomes than other cells in the body. Besides their primary role in breaking down complex organic molecules, peroxisomes can also synthesize specific macromolecules and participate in...

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Hydrogen Peroxide Quantification Using Zero Dimensional Carbon Nanostructured Materials: A Review.

Priti Sharma1, Sopan N Nangare2, Shashikant B Bagade3

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Critical Reviews in Analytical Chemistry
|December 3, 2024
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Summary

Hydrogen peroxide (H2O2) is linked to cancer and health issues. This review highlights graphene quantum dots (GQDs) and carbon quantum dots (CQDs) as advanced nanomaterials for sensitive H2O2 detection in bioanalysis and environmental monitoring.

Keywords:
Carbon nanomaterialscarbon quantum dotsfluorescent probes graphene quantum dotshydrogen peroxide

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Area of Science:

  • Nanomaterials Science
  • Analytical Chemistry
  • Biomedical Sensing

Background:

  • Hydrogen peroxide (H2O2) is implicated in various health conditions, including cancer, cardiovascular disease, and neurodegenerative disorders.
  • Accurate and rapid detection of H2O2 is crucial for bioanalysis, environmental protection, and food security.
  • Traditional H2O2 detection methods face limitations in sensitivity and specificity.

Purpose of the Study:

  • To review recent advancements in sensing systems utilizing graphene quantum dots (GQDs) and carbon quantum dots (CQDs) for H2O2 detection.
  • To explore the enhanced H2O2 detection capabilities offered by these carbon-based nanomaterials.
  • To discuss the period from 2015 to 2024 regarding GQD and CQD-based H2O2 sensors.

Main Methods:

  • Review of literature focusing on the application of zero-dimensional (0D) carbon-based nanostructures (GQDs and CQDs) as fluorescent probes.
  • Analysis of sensing mechanisms employed by GQD and CQD-based sensors, including photoinduced electron transfer (PET), inner filter effect (IFF), static and dynamic quenching, and Förster resonance energy transfer (FRET).
  • Evaluation of the unique electrical, fluorescent, photoluminescent, chemiluminescent, and electrochemiluminescent properties of GQDs and CQDs for sensing applications.

Main Results:

  • GQDs and CQDs exhibit remarkable potential for H2O2 sensing due to their distinctive optoelectronic properties.
  • Various carbon-based sensor designs utilizing mechanisms like quenching and energy transfer have demonstrated high sensitivity and selectivity for H2O2.
  • The review covers innovative applications of GQDs and CQDs in H2O2 detection from 2015 to 2024.

Conclusions:

  • Carbon-based nanoscale sensors, particularly those employing GQDs and CQDs, offer highly effective and precise options for H2O2 detection.
  • GQD and CQD-based nanosystems provide a novel platform for H2O2 recognition, paving the way for improved health diagnostics and environmental monitoring.
  • These advanced nanomaterials hold promise for point-of-care diagnostics and real-time monitoring of environmental processes.