Philippine guidelines on the dietary primary prevention of allergic diseases in children
Related Experiment Video
Updated: Jun 6, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Roxanne J Casis Hao1, Maria Lourdes G Genuino1, Carol Stephanie C Tan-Lim1
1Department of Pediatrics, University of the Philippines Manila-Philippine General Hospital, Manila, Philippines.
Insights
New guidelines offer dietary strategies for preventing pediatric allergic diseases in the Philippines. Evidence certainty varies, highlighting research gaps in optimal food interventions for children.
Area of Science:
- Allergy and Immunology
- Pediatric Gastroenterology
- Clinical Practice Guidelines
Background:
- Rising prevalence of pediatric allergic diseases in the Philippines.
- Need for updated clinical guidance on prevention.
- Joint effort by the Philippine Society of Allergy, Asthma, and Immunology (PSAAI) and the Philippine Society of Pediatric Gastroenterology, Hepatology, and Nutrition (PSPGHAN).
Purpose of the Study:
- To update recommendations for clinicians on dietary interventions for preventing allergic diseases in children.
- Provide evidence-based guidance for managing pediatric allergies.
- Address the growing public health concern of childhood allergies.
Main Methods:
- Systematic search and appraisal of existing clinical practice guidelines and systematic reviews.
- Adherence to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.
- Conduct of a de novo systematic review when necessary, followed by consensus-based recommendations.
Main Results:
- Recommendations formulated based on evidence of benefits, harms, cost, feasibility, acceptability, and availability.
- Identified significant research gaps impacting the certainty of evidence for many dietary recommendations.
- Consensus panel reviewed evidence summaries to formulate recommendations.
Conclusions:
- The guidelines provide updated recommendations for the dietary prevention of pediatric allergic diseases.
- Low certainty of evidence exists for several dietary interventions, underscoring the need for further research.
- Clinical practice should consider the available evidence and identified limitations when implementing dietary strategies.
Background:
In response to the continual increase in the prevalence of pediatric allergic diseases in the Philippines, the Philippine Society of Allergy, Asthma, and Immunology (PSAAI) and the Philippine Society of Pediatric Gastroenterology, Hepatology, and Nutrition (PSPGHAN) have published guidelines on the dietary prevention of allergic diseases in children.
Objective:
This guideline aims to update the previous guideline recommendations for clinicians on the use of dietary interventions for the prevention of allergic disease in children.
Methods:
Following the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach specified in the Department of Health Manual for Clinical Practice Guidelines development, we systematically searched for and appraised clinical practice guidelines and systematic reviews on topics formulated and prioritized by a Steering Committee, which comprised of members of the PSAAI and PSPGHAN. In the absence of an existing systematic review, a de novo systematic review was conducted. A multisectoral consensus panel reviewed the evidence summaries and formulated recommendations through a formal consensus method.
Results And Conclusion:
The recommendations made by the consensus panel were based on the available evidence on the benefits and harm of the intervention, as well as the cost, feasibility, acceptability, and availability. Several research gaps exist, resulting in low levels of certainty of evidence on most dietary recommendations for the prevention of pediatric allergic diseases.
Related Concept Videos
Primary Healthcare Services
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
Preventive Healthcare Services
Allergic Reactions
Asthma-I: Introduction
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...

