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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Sunscreens: A narrative review.

Hamisha Salih1, Cristina Psomadakis1, Susannah M C George1

  • 1University Hospitals Sussex NHS Foundation Trust Brighton UK.

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This summary is machine-generated.

Sunscreens protect skin from ultraviolet radiation (UVR), but concerns exist regarding their safety and environmental impact. This review covers sunscreen history, types, ratings, and controversies for informed choices.

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Area of Science:

  • Dermatology
  • Environmental Science
  • Toxicology

Background:

  • Sunscreens are topical products designed to protect the skin from harmful ultraviolet radiation (UVR).
  • Their use is widely recommended to prevent sunburn, skin cancer, and premature aging caused by sun exposure.
  • Despite benefits, concerns about the safety and environmental effects of sunscreens and their ingredients are growing.

Purpose of the Study:

  • To provide a comprehensive overview of sunscreens, including their historical development.
  • To detail the various types of UV filters used in sunscreen formulations.
  • To explore the controversies surrounding sunscreen safety and environmental impact.

Main Methods:

  • This study is a narrative review of existing literature on sunscreens.
  • It synthesizes information on sunscreen history, UV filter classification, and rating systems.
  • It also examines reported safety and environmental concerns.

Main Results:

  • Sunscreens have evolved significantly, with diverse UV filters available.
  • Current classifications and ratings help consumers choose products.
  • Controversies include potential endocrine disruption, allergic reactions, and ecotoxicity.

Conclusions:

  • Understanding sunscreen history, types, and controversies is crucial for informed consumer decisions.
  • Further research is needed to address safety and environmental concerns.
  • Balancing sun protection with potential risks is essential.