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[Therapeutic problems after massive blood transfusions].

M Wendt, P Lawin, E Götz

    Infusionstherapie Und Klinische Ernahrung
    |December 1, 1979
    PubMed
    Summary
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    Massive blood transfusions present ongoing challenges despite microfilter use, including shock-induced respiratory issues and managing fluid balance. Early ventilation is crucial for patient recovery during and after transfusion.

    Area of Science:

    • Transfusion Medicine
    • Critical Care Medicine
    • Hematology

    Background:

    • The definition of massive blood transfusion remains unclear.
    • Microfilters have improved clinical outcomes but persistent shock can lead to acute respiratory distress.
    • Challenges include buffering, erythrocyte function, fluid/electrolyte balance, renal function, and coagulation.

    Purpose of the Study:

    • To review the persistent challenges and management strategies associated with massive blood transfusions.
    • To highlight the importance of early and adequate ventilation in massive transfusion protocols.

    Main Methods:

    • Literature review of massive blood transfusion complications and management.
    • Discussion of pre-transfusion warming and patient rewarming techniques.

    Related Experiment Videos

  • Emphasis on monitoring renal function and coagulation status.

    • Main Results:

    • Microfilters have reduced complications, but shock remains a risk factor for respiratory disease.
    • Stored blood exhibits slow erythrocyte activation, impacting oxygen delivery.
    • Proper fluid and electrolyte management is essential.

    Conclusions:

    • Massive blood transfusion requires careful management of physiological parameters.
    • Early and sustained ventilation is critical for mitigating respiratory complications.
    • Addressing buffering, erythrocyte function, and fluid balance is key to optimizing outcomes.