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[Necrotizing pneumonia in a patient with selective IgA deficiency]
María Enriqueta Núnez-Núñez1, Denisse Monraz-Monteón2, Juan Carlos Lona-Reyes3
1Servicio de Inmunología-Alergología, Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Jalisco.
This case highlights a severe infection in a 4-year-old boy, leading to the diagnosis of selective IgA deficiency, a type of inborn error of immunity.
Area of Science:
- Pediatrics
- Immunology
- Genetics
Background:
- Inborn errors of immunity (IEI) stem from monogenic mutations.
- IEI should be considered in patients with recurrent infections, allergies, autoimmunity, autoinflammatory diseases, bone marrow failure, and malignancy.
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