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Updated: Jun 16, 2025
08:19
A Spheroid Killing Assay by CAR T Cells
Published on: December 12, 2018
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RORing CAR T Cells in Solid and Hematologic Cancers: Same but Different
Sebastian Kobold1,2,3
1Division of Clinical Pharmacology, LMU University Hospital, LMU Munich, Munich, Germany.
Abstract:
A recent phase I clinical study tested anti-ROR1 chimeric antigen receptor (CAR) T cells in patients with chronic lymphocytic leukemia, non-small cell lung cancer, and triple-negative breast cancer. The product could be safely administered and had activity in chronic lymphocytic leukemia but less so in non-small cell lung cancer and triple-negative breast cancer. See related article by Jaeger-Ruckstuhl et al., p. 503.
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