Related Experiment Video
Updated: Jun 6, 2025
09:52
Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
26.8K
Management of Twin Reversed Arterial Perfusion Sequence: A Systematic Review and Meta-Analysis
Michael A Stellon1, Devashish S Joshi2, Michael J Beninati3
1Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA, mstellon@uwhealth.org.
Fetal Diagnosis and Therapy
|December 3, 2024
Summary
Radiofrequency ablation (RFA) is the most technically successful treatment for twin reversed arterial perfusion (TRAP) sequence. While pump twin survival is similar across methods, RFA offers better outcomes for this rare twin pregnancy complication.
Area of Science:
- Maternal-Fetal Medicine
- Reproductive Medicine
- Obstetrics
Background:
- Twin reversed arterial perfusion (TRAP) sequence is a rare complication of monochorionic twin pregnancies.
- It involves placental anastomoses between a normal twin and an acardiac mass.
- Optimal management strategies for TRAP sequence remain unclear.
Purpose of the Study:
- To compare the effectiveness and outcomes of various treatment strategies for TRAP sequence.
- To identify the most technically successful intervention for TRAP sequence.
Main Methods:
- A systematic review and meta-analysis adhering to PRISMA guidelines.
- Literature search across PubMed, Scopus, Web of Science, and Cochrane Library.
- Statistical analysis using Fisher's exact test and random effects modeling.
Main Results:
- Radiofrequency ablation (RFA) demonstrated the highest technical success rate.
- No significant differences in pump twin survival were observed across treatment modalities.
- Suture cord ligation was associated with a higher hemorrhage rate compared to RFA.
Conclusions:
- RFA is the most technically successful strategy for TRAP sequence.
- Further prospective studies are needed to determine the optimal treatment modality and gestational age for best outcomes.
Related Concept Videos
01:17Aortic Regurgitation IV: Nursing Management
9
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
9
01:14Fetal Circulation
810
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
810