Development of soybean protein-based bioactive substances delivery systems: A systematic overview based on recent...

Some bioactive substances in food have problems such as poor solubility, unstable chemical properties and low bioavailability, which limit their application in functional foods. In recent years, in order to improve the above problems of bioactive substances, soybean protein-based drug delivery systems have been developed. This article reviewed the structure and properties of several major soybean protein commonly used to construct bioactive substance delivery systems. Several common carrier types based on soybean protein were then introduced. The biological functions and limitations of several common soybean protein delivery bioactive substances and the role of soybean protein-based delivery systems were discussed. At present, soybean protein is the most widely used in drug delivery systems. Soybean protein-based nano-particles are currently the most commonly used delivery carriers. Soybean protein-based hydrogels, emulsions, microcapsules and electrospinning are also widely used. Polyphenols, carotenoids, vitamins, functional oils and probiotics are bioactive substances that are frequently delivered. However, in order to promote the application of soybean protein-based delivery systems in food, soybean protein peptidyl delivery vectors and collaborative delivery are the future development trends. In addition, a number of challenges must be addressed, including the sensitization of soybean protein, intolerance to environmental conditions, and the limitations of processing technologies.