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Updated: Jun 6, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
A prospective study on the effect of reoperations on abdominal pain after bariatric surgery: the OPERATE study
Daniko P Sindhunata1, Marjolein R A Vink1, Barbara A Hutten2
1Department of Internal and Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Bariatric Surgery, Spaarne Gasthuis, Hoofddorp, the Netherlands.
Background:
Abdominal pain after bariatric surgery (BS) is not uncommon. A number of patients require reoperation. Limited studies have investigated the outcome of reoperations for abdominal pain after BS.
Objectives:
To assess abdominal pain and quality of life after reoperation in patients with abdominal pain after BS.
Setting:
Bariatric center in the Netherlands.
Methods:
The study involved patients with a reoperation for abdominal pain after BS. Patients completed questionnaires on abdominal complaints and quality of life after inclusion, 3 months, and 6 months after reoperation. Clinical data were collected from records. Patients were compared on the basis of preoperative provisional diagnoses and postoperative diagnoses.
Results:
A total of 179 patients were included, with laparoscopic Roux-en-Y gastric bypass (86.0%), at a median of 27 months [9.5-76.0] after BS. Six months after reoperation, 51.6% continued to experience pain. However, a decline in pain severity was observed (visual analog scale baseline 83.50 [75.0-95.0] and 6 months 0 [.0-44.0] (P < .001). Patients without postoperative diagnosis had more pain after 6 months (P = .048). Gastrointestinal Quality of Life Index improved over time for all patients (94-110) (P < .001); however, no significant improvement was observed in patients without a preoperative provisional diagnosis. The general indication of health decreased for all patients (P < .001).
Conclusions:
Abdominal pain intensity decreased during follow-up upon reoperation after BS; however, in approximately one half of the patients, the pain remained and a decline in general health indication was observed regardless of postoperative diagnosis. These findings underscore the need for comprehensive management strategies to address post-BS pain and well-being.
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