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Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

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Updated: May 7, 2026

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation
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[Spatial Distribution, Source Analysis, and Risk Assessment of Multiple Antibiotics in Chaohu Lake Basin].

Hai-Xin Wu1, Yu-Yu Sun1, Gui-Jian Liu2

  • 1School of Life Sciences, University of Science and Technology of China, Hefei 230026, China.

Huan Jing Ke Xue= Huanjing Kexue
|December 4, 2024
PubMed
Summary

Antibiotic pollution in China's Chaohu Lake was studied. High risks to algae from norfloxacin were found, with livestock and household sewage identified as primary sources.

Keywords:
Chaohu Lakeantibioticsecological risk assessmenthealth risk assessmentsource analysisspatial distribution

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Area of Science:

  • Environmental Chemistry
  • Ecotoxicology
  • Analytical Chemistry

Context:

  • Chaohu Lake, China's fifth-largest freshwater lake, is vital for socio-economic development and ecological health.
  • It supports industries, tourism, and flood storage, and harbors habitats for rare birds.
  • Understanding antibiotic pollution is crucial for its eco-economic importance.

Purpose:

  • To investigate the occurrence, spatial distribution, and sources of antibiotic contamination in Chaohu Lake.
  • To assess the ecological and health risks associated with identified antibiotics.
  • To provide data for effective pollution control and management strategies.

Summary:

  • 20 antibiotics, including sulfonamides, quinolones, macrolides, and tetracyclines, were detected in surface water and sediments.
  • Significant spatial variations were observed, with consistent vertical distribution patterns in some cases.
  • Principal component analysis linked pollution sources to livestock, aquaculture, and domestic sewage.

Impact:

  • Norfloxacin poses a high ecological risk to algae; sulfamethoxazole and doxycycline pose medium risks.
  • Health risks from drinking water are very low.
  • Findings support policymakers in managing antibiotic pollution and reducing watershed management costs.