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  • 0Division of Geriatrics and Palliative Care, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.

Summary

No abstract available on PubMed

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Overview

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.

Errors during Replication Are Corrected by the DNA Polymerase Enzyme

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