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Longer Preoperative Antibiotic Duration Prior to High-Risk Ureteroscopy Does Not Decrease Infectious Complications.

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Summary
This summary is machine-generated.

For patients undergoing ureteroscopy, preoperative antibiotic duration did not impact postoperative infection rates. Women showed a higher risk of urinary tract infections (UTIs) and pyelonephritis.

Keywords:
antibacterial agentsnephrolithiasissystemic inflammatory response syndromeureteroscopyurinary tract infections

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Area of Science:

  • Urology
  • Infectious Diseases
  • Surgical Outcomes

Background:

  • Postoperative infections are common after ureteroscopy.
  • Management of asymptomatic bacteriuria before ureteroscopy is unclear.
  • Antibiotic practices vary widely for high-risk patients.

Purpose of the Study:

  • To evaluate the impact of preoperative antibiotic duration on postoperative infection rates in high-risk patients undergoing ureteroscopy.
  • To identify clinical factors associated with postoperative infectious complications.

Main Methods:

  • Retrospective analysis of a prospectively collected database (2015-2023).
  • Included high-risk patients undergoing ureteroscopy with documented urine cultures.
  • Assessed correlation between preoperative antibiotic duration and infectious complications (UTI, pyelonephritis, SIRS, fever).

Main Results:

  • 405 high-risk patients were analyzed.
  • 68% received no preoperative antibiotics; 21% received varying durations.
  • No significant association between antibiotic duration and infection rates; women had higher UTI/pyelonephritis risk (OR 4.135).

Conclusions:

  • Preoperative antibiotic duration did not influence postoperative infection rates in high-risk ureteroscopy patients.
  • Female sex is a significant risk factor for postoperative urinary tract infections.
  • Further research is needed for effective infection prevention strategies.