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BAD2matrix: Phylogenomic matrix concatenation, indel coding, and more.

Nelson R Salinas1, Gil Eshel2, Gloria M Coruzzi2

  • 1Lewis B. and Dorothy Cullman Program for Molecular Systematics The New York Botanical Garden, Bronx New York USA.

Applications in Plant Sciences
|December 4, 2024
PubMed
Summary
This summary is machine-generated.

A new Python script, BAD2matrix, simplifies phylogenomic matrix construction. It automates common steps for DNA, amino acid, and morphological data, streamlining complex analyses.

Keywords:
concatenationgene contentgene presence/absenceindel codingmorphologyoccupancy filteringphylogenomicsreduced amino acid alphabets

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Area of Science:

  • Computational Biology
  • Bioinformatics
  • Evolutionary Biology

Background:

  • Phylogenomic matrix construction involves multiple complex steps.
  • Existing software often requires multiple programs for these tasks.
  • There is a need for integrated tools to simplify phylogenomic analyses.

Purpose of the Study:

  • To develop a single program for comprehensive phylogenomic matrix production.
  • To automate key steps in creating phylogenomic datasets.
  • To provide a user-friendly tool for researchers in evolutionary biology.

Main Methods:

  • Developed BAD2matrix, a Python script for phylogenomic matrix construction.
  • The script handles DNA, amino acid, and morphological data.
  • It integrates common steps like sequence concatenation, indel coding, and occupancy filtering.

Main Results:

  • BAD2matrix successfully automates multiple phylogenomic matrix production steps.
  • The script is compatible with UNIX-like environments.
  • It simplifies complex phylogenomic data preparation pipelines.

Conclusions:

  • BAD2matrix offers a unified solution for phylogenomic matrix construction.
  • The script enhances efficiency in bioinformatics workflows.
  • It is available under a GNU General Public License v2.