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Biopolymer encapsulation for improved probiotic delivery: Advancements and challenges
Srirengaraj Vijayaram1, Reshma Sinha2, Caterina Faggio3
1Department of Veterinary Medicine, College of Veterinary Medicine, National Chung-Hsing University, 145 Xingda Rd. Taichung, 40227, Taiwan.
AIMS Microbiology
|December 4, 2024
Summary
Biopolymers enhance probiotic delivery and survival through advanced encapsulation techniques. These methods improve stability and effectiveness for various applications, overcoming limitations in challenging environments.
Area of Science:
- Biotechnology and Materials Science
- Microbiology and Food Science
Background:
- Probiotics are beneficial microorganisms crucial for agriculture, aquaculture, nutraceuticals, and pharmaceuticals.
- Effective delivery and storage are vital for maximizing probiotic efficacy.
- Biopolymers offer stability, biocompatibility, and biodegradability, ideal for enhancing probiotic capabilities.
Purpose of the Study:
- To review advancements in biopolymer-based probiotic encapsulation materials and techniques.
- To address limitations in current methods regarding probiotic viability under extreme conditions.
- To explore customized encapsulation for enhanced probiotic stability, survival, and targeted delivery.
Main Methods:
- Comprehensive review of various biopolymer encapsulation techniques (e.g., spray drying, electrospinning, layer-by-layer assembly).
- Comparative analysis of encapsulation method effectiveness in challenging environments (high temperature, acidity, gastrointestinal transit).
- Focus on biopolymer-probiotic interactions to optimize stability and functionality.
Main Results:
- Novel encapsulation methods, including biopolymer blends and advanced techniques like electrospinning, show superior performance.
- Enhanced protection and controlled release of probiotics are achieved through customized biopolymer systems.
- Biopolymer encapsulation significantly improves probiotic stability, survival, and bioavailability.
Conclusions:
- Biopolymer-based encapsulation is key to overcoming challenges in probiotic delivery.
- Advanced techniques offer robust systems for sustained probiotic viability and bioavailability.
- This review provides a foundation for refining encapsulation for clinical and commercial applications.
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