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Published on: September 22, 2023
Fundoplication for Pediatric Gastroesophageal Reflux Disease: Indications, Techniques, and Outcomes
Maimona A Al-Refaie1, Mohammed M Alsurmi2, Yasser A Obadiel3
1Department of Pediatric Surgery, Al-Thawra Modern General Hospital, Sana'a, YEM.
Insights
Fundoplication surgery effectively treats pediatric gastroesophageal reflux disease (GERD), achieving symptom resolution in most patients. Postoperative esophageal strictures require management with dilatation protocols for optimal outcomes.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Outcomes Research
Background:
- Gastroesophageal reflux disease (GERD) is a common condition in pediatric patients.
- Surgical intervention, such as fundoplication, is considered for severe or refractory GERD.
- Evaluating the safety and efficacy of fundoplication in pediatric populations is crucial.
Purpose of the Study:
- To assess the indications, surgical techniques, and outcomes of fundoplication in pediatric GERD patients.
- To analyze postoperative complications and their management.
- To determine the overall effectiveness of fundoplication in a tertiary hospital setting in Yemen.
Main Methods:
- A prospective cohort study involving 45 pediatric patients (<18 years) undergoing fundoplication for GERD.
- Data collection included demographics, clinical characteristics, surgical type (Nissen or Thal), complications, and follow-up.
- Statistical analysis of collected data to evaluate outcomes and complications.
Main Results:
- Nissen fundoplication (80%) was more common than Thal fundoplication (20%).
- Complete symptom resolution was achieved in 68.89% of patients.
- The most frequent complication was dysphagia due to postoperative esophageal stricture (29%), managed with dilatation.
Conclusions:
- Fundoplication is a safe and effective surgical option for pediatric GERD, yielding high success rates.
- Structured postoperative dilatation protocols are vital for managing esophageal strictures and improving patient outcomes.
- Early diagnosis, intervention, and adherence to postoperative care are key for optimal results in pediatric fundoplication.
Abstract:
Background This study aimed to evaluate the indications, techniques, and outcomes of fundoplication in pediatric patients with gastroesophageal reflux disease (GERD) at a tertiary hospital in Yemen. Methods A prospective cohort study was conducted at Al-Thawra Modern General Hospital, Sana'a, Yemen, between January 2015 and January 2022. The study included 45 pediatric patients under 18 years of age who underwent fundoplication for GERD. Data on demographic and clinical characteristics, surgical type, postoperative complications, and follow-up outcomes were collected and analyzed. Results The median age of the 45 pediatric patients was two years (range: two months to 10 years), with 25 males (56%) and 20 females (44%). The primary indications for fundoplication included GERD with hiatal hernia in 20 patients (44.4%), persistent symptoms despite medical management in 9 patients (20%), recurrent chest infections associated with neurological disorders in 7 patients (15.6%), esophageal stricture in 8 patients (17.8%), and both hiatal hernia and esophageal stricture in 1 patient (2.2%). Nissen fundoplication was performed in 36 patients (80%), and Thal fundoplication was performed in 9 patients (20%). Complete symptom resolution was achieved in 31 patients (68.89%). Dysphagia due to postoperative esophageal stricture was the most common complication, affecting 13 patients (29%). A structured dilatation protocol resulted in improvement after one session in four patients (30.8%), regular sessions in six patients (46.2%), and irregular sessions in three patients (23.1%). The mortality rate was two patients (5.56%), both of whom had cerebral palsy and died due to recurrent chest infections unrelated to GERD recurrence or esophageal stricture. Conclusions Fundoplication is a safe and effective surgical treatment for pediatric GERD, with a high success rate and manageable complications. A structured postoperative dilatation protocol is essential for managing esophageal strictures and improving outcomes. Early diagnosis and intervention, alongside adherence to postoperative protocols, are crucial for optimal results. Further research with larger sample sizes and long-term follow-up is recommended to confirm these findings and improve clinical practice.
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