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Updated: Jun 5, 2025

Isolation and Characterization of Intact Phycobilisome in Cyanobacteria
Published on: November 10, 2021
A study of the protein-protein interactions in the phycocyanin monomer from Synechocystis sp. PCC 6803 using a
Simi Shao1, Longsheng Zhao1, Pingyi Li1
1State Key Laboratory of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Qingdao 266237, China.
Abstract:
Investigations into the intramolecular interactions of the native protein in solution are important to understand its structural stability as well as its potential uses in future applications. In this study, we used a bacterial two-hybrid system to investigate the interaction between the phycocyanin α and β subunits that form the phycocyanin monomer. Key amino acid residues responsible for the interaction between the subunits were identified, providing direct experimental evidence for the intramolecular interaction.
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