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Updated: Jun 5, 2025

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Iterative smoothing for change-point regression function estimation
1Department of Computer Science, Mathematics, Physics and Statistics, University of British Columbia, Kelowna, British Columbia, Canada.
Abstract:
Understanding wildfire spread in Canada is critical to promoting forest health and protecting human life and infrastructure. Quantifying fire spread from noisy images, where change-point boundaries separate regions of fire, is critical to accurately estimating fire spread rates. The challenge lies in denoising the fire images and accurately identifying highly non-linear fire lines without smoothing over boundaries. In this paper, we develop an iterative smoothing algorithm for change-point data that utilizes oversmoothed estimates of the underlying data generating process to inform re-smoothing. We demonstrate its effectiveness on simulated one- and two-dimensional change-point data, and robustness to response outliers. Then, we apply the methodology to fire spread images from laboratory micro-fire experiments and show that the regions fuel, burning and burnt-out are smoothed while boundaries are preserved.
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