Related Experiment Video
Updated: Jun 5, 2025
A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
Published on: November 2, 2019
PSMA Accumulation in Lower Extremity Lymphedema and Hydrocele
Merve Nida Calderon Tobar1, Lutfi Perktas, Hasan Önner
1From the Department of Nuclear Medicine, Faculty of Medicine, Selcuk University, Konya, Turkey.
Abstract:
The development of radiolabeled small-molecule prostate-specific membrane antigen (PSMA) inhibitors has advanced molecular imaging in prostate cancer. The use of 177 Lu-PSMA is especially beneficial because its therapeutic β-emission combined with γ-radiation enables precise treatment and comprehensive imaging in patients with prostate cancer. We present a case of a prostate cancer patient who developed lower extremity lymphedema and hydrocele secondary to prior radiotherapy. Posttherapy whole-body imaging following 177 Lu-PSMA treatment revealed dermal backflow with a notable accumulation of soft tissue in the lower extremities and hydrocele.
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