Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

Types of Step-Growth Polymers: Polyesters

2.2K
The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the...
2.2K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

1.9K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
1.9K
Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

2.1K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.1K
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

3.4K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
3.4K
Free-Radical Chain Reaction and Polymerization of Alkenes02:35

Free-Radical Chain Reaction and Polymerization of Alkenes

7.7K
The conversion of alkenes to macromolecules called polymers is a reaction of high commercial importance. The structure of the polymer is defined by a repeating unit, while the terminal groups are considered insignificant. The average degree of polymerization represents the number of repeating units in the polymer molecule and is denoted by the subscript n.
7.7K
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

2.6K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of poly(ester disulfide)s from S<sub>8</sub>-involved step-growth addition polymerization at ambient temperature.

Nature communications·2026
Same author

Iron-Catalyzed Synthesis of Unsymmetrical Disilanes.

Journal of the American Chemical Society·2026
Same author

A Versatile Platform for Recyclable Polyesters: Alternating Copolymerization of Aldehydes (or Their Derivatives) with Cyclic Anhydrides.

Accounts of chemical research·2025
Same author

Intramolecular Hydrogen-Bonding Catalyst/Initiator for Precise Synthesis of Polycarbonates and Copolymers with Unprecedented Activity and Molecular Weights.

Angewandte Chemie (International ed. in English)·2025
Same author

Nonconjugated Polyesters Emitting Full-Color Clusteroluminescence.

Accounts of chemical research·2025
Same author

Detection of β-transition in polyesters <i>via</i> clusteroluminescence.

Materials horizons·2025

Related Experiment Video

Updated: Jun 5, 2025

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.1K

Autodegradable Polymers: Complete Degradation without Any Trigger, Tunable Performance, and Biomedical Applications.

Shuohong Chen1, Chengjian Zhang1, Xinghong Zhang1

  • 1State Key Laboratory of Biobased Transportation Fuel Technology, International Research Center for X Polymers, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.

Journal of the American Chemical Society
|December 4, 2024
PubMed
Summary
This summary is machine-generated.

New degradable polymers were synthesized for drug delivery. These polymers self-degrade completely without triggers, offering tunable degradation rates for biomedical applications.

More Related Videos

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

13.4K
Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.0K

Related Experiment Videos

Last Updated: Jun 5, 2025

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

19.1K
Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

13.4K
Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

5.0K

Area of Science:

  • Polymer Chemistry
  • Biomaterials Science

Background:

  • Developing degradable polymers for biomedical use is complex.
  • Key challenges include ensuring nontoxicity, complete degradation, and suitable material properties.

Purpose of the Study:

  • To synthesize novel degradable polymers for sustained drug delivery.
  • To explore their unique degradation mechanisms and properties for biomedical applications.

Main Methods:

  • Alternating copolymerization of cyclic anhydrides and Schiff bases.
  • Characterization of polymer structure, including cyclic topologies and in-chain ester/peptoid groups.
  • Assessment of self- and autodegradation behavior under varying conditions.

Main Results:

  • Successfully synthesized versatile, catalyst-free degradable polymers.
  • Demonstrated unique self- and autodegradation without external triggers.
  • Achieved tunable degradation rates from hours to months, controlled by polymer structure and temperature.
  • Validated polymer safety and efficacy through cell viability assays and in vitro/in vivo drug release studies.

Conclusions:

  • The novel degradable polymers show promise for sustained drug delivery.
  • Their inherent self-degradation and tunable properties make them suitable for biomedical applications.
  • Further research can explore diverse applications based on these unique degradable polymer systems.