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Diagnostic Performance of Artificial Intelligence-Based Angiography-Derived Non-Hyperemic Pressure Ratio Using
Hiroyuki Omori1,2, Yoshiaki Kawase1, Takuya Mizukami1,3
1Department of Cardiovascular Medicine, Gifu Heart Center.
Summary
Artificial intelligence-derived non-hyperemic pressure ratio (angioNHPR) accurately detects coronary artery disease without pressure wires. This novel AI tool shows diagnostic performance comparable to invasive methods, improving non-invasive assessments.
Area of Science:
- Cardiology
- Medical Imaging
- Artificial Intelligence in Medicine
Background:
- The angiography-derived non-hyperemic pressure ratio (angioNHPR) is a novel index for assessing coronary artery disease.
- It utilizes artificial intelligence (AI) and does not require invasive pressure wires.
Purpose of the Study:
- To investigate the diagnostic accuracy of angioNHPR for detecting hemodynamically relevant coronary artery disease.
- To compare angioNHPR performance against invasive non-hyperemic pressure ratio (NHPR).
Main Methods:
- Retrospective single-center study involving 222 vessels from 178 patients.
- AI software automatically segmented lumen and centerline from two angiographic projections.
- angioNHPR was calculated and compared with invasive NHPR as the reference standard.
Main Results:
- angioNHPR demonstrated an accuracy of 76.6% and an area under the curve (AUC) of 0.81.
- It showed good correlation (r=0.72) and agreement with invasive NHPR.
- The AUC of angioNHPR was significantly higher than 2D quantitative coronary angiography (0.69).
Conclusions:
- AI-based angioNHPR shows good diagnostic performance for detecting physiologically significant stenosis.
- This non-invasive method offers a promising alternative to pressure wire-based assessments.
- angioNHPR represents a significant advancement in non-invasive coronary artery disease evaluation.
Related Concept Videos
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The Brachial Artery: Primary Site for Blood Pressure Measurement
The Brachial Artery: Primary Site for Blood Pressure Measurement
01:30Equipments Used To Measure Blood Pressure
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
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01:28Special considerations while measuring blood pressure
When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
01:10Pre-Procedural Guidelines for Assessing Blood Pressure
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
01:17Measurement of Blood Pressure
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.