Treatment options for chronic hypotony: a scoping review protocol

Area of Science:

• Ophthalmology
• Medical Research

Background:

• Chronic ocular hypotony, defined as intraocular pressure (IOP) of 6.5 mm Hg or less for at least 3 months, is a vision-threatening condition.
• Limited data exists on the management of chronic ocular hypotony, leading to a lack of standardized treatment protocols and unclear visual prognoses.

Purpose of the Study:

• To conduct a scoping review of existing literature on the medical and surgical management of chronic ocular hypotony.
• To identify and synthesize current treatment approaches and outcomes for patients with low intraocular pressure.

Main Methods:

• A comprehensive scoping review protocol following JBI best practices.
• Searches of major databases (Ovid Medline, Embase, Cochrane, Web of Science, Scopus) and grey literature using keywords 'Ocular hypotony,' 'medication,' and 'surgery.'
• Narrative synthesis of data from eligible studies on adult patients undergoing medical or surgical treatment.

Main Results:

• Data charting using a custom Microsoft Excel form.
• Findings will be grouped by treatment type and outcomes.
• A narrative summary of treatment strategies and their associated outcomes for chronic ocular hypotony.

Conclusions:

• This review addresses the paucity of data in managing chronic ocular hypotony.
• It aims to provide a foundation for future research and potential guideline development.
• Findings will be disseminated through open-access publication and international meetings.